Tricyclo[6.2.1.02,7]undeca-4,9-diene-3,6-dione
نویسنده
چکیده
The title compound, C(11)H(10)O(2), crystallizes with two independent mol-ecules in the asymmetric unit. In one mol-ecule, the dihedral angle between the mean planes of the C-C=C-C group of the diene unit and essentially planar cyclo-hexene ring is 51.07 (9)°, while in the other mol-ecule it is 54.49 (12)°. In the crystal structure, weak inter-molecular C-H⋯O inter-actions link the mol-ecules into columns along the b axis.
منابع مشابه
5-Methyl-2,4-bis(methylsulfanyl)tricyclo[6.2.1.02,7]undeca-4,9-diene-3,6-dione1
The structure analysis of the title compound, C(14)H(16)O(2)S(2), shows the SMe and H atoms of the bond linking the six-membered rings to be syn and also to be syn to the bridgehead -CH(2)- group. Each of the five-membered rings adopts an envelope conformation at the bridgehead -CH(2)- group. The dione-substituted ring adopts a folded conformation about the 1,4-C⋯C vector, with the ketone group...
متن کاملSynthesis and biological evaluation of rigid polycyclic derivatives of the Diels-Alder adduct tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione.
Part of our research program concentrates on the discovery of new bioactive compounds prepared either by total synthesis or molecular transformation of compounds with bioactivity profiles. In this work we have focused our interest on chemical transformations of the Diels-Alder adduct tricyclo[6.2.1.0(2,7)]undeca-4,9-dien-3,6-dione in order to obtain cage-like compounds and derivatives, followed...
متن کاملBiotransformation of a cage-like diels-alder adduct and derivatives by Mucor ramosissimus samutsevitsch
The present study aimed to evaluate the ability for biotransformation of the Diels-Alder adduct tricyclo[6.2.1.0(2,7)]undeca-4,9-dien-3,6-dione (1) and two synthetic derivatives by the saprobe fungus Mucor ramosissimus Samutsevitsch. Products from oxidation, isomerization and, regioselective and enantioselective reduction were achieved.
متن کاملComparison of [3H]progesterone and [6,7-3H]-17,21-dimethyl-19-norpregna-4,9-diene-3,20-dione for the measurement of progesterone receptors in human malignant tissue.
Progesteronereceptorsof humantumorsof breast and gynecologicaloriginwere assayed with [6,7-3H]-17,21-di methyb-19-norpregna-4,9-diene-3,20-dione or [1,2,6,7-3H]progesterone plus a 100-fold excess of cortisol by the charcoal extraction method. Whereas both ligands gave concordantlevels of bindingfor the high-capacitysam pies,highernonspecific bindingof I 7,21-dimethyl-1 9-nor pregna-4,9-diene-3,...
متن کاملDeposited in DRO : 08
The preparation of a number of alkyl and alkoxy derivatives of pentacyclo[5.4.0.0.0.0]undecane8,11-dione derivatives utilising a cheap, practical, low energy, “green”, single-pass continuous flow photochemical reactor is reported Their H and C NMR spectra are fully assigned, revealing some general characteristics not previously reported for this class of compound, which should aid the assignmen...
متن کامل